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New Antibody: Mouse anti-Desmin, clone BS21

Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate
filament family and Desmin is class III intermediate filaments found in muscle cells.

Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

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0.1 ml format, MON5158-0.1
1.0 ml format, MON5158-1
7.0 ml format, MON-RTU5158 (Ready to use)


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