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The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117), which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST), small lung cell carcinomas and in melanomas.
Specifications
Applications
IHC-P
Host
Rabbit
Clonality
Monoclonal
Clone
EP10
Supplier
MONOSAN Xtra
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C