The CD71 molecule is a type II membrane glycoprotein with a molecular weight of approximately 180 kD. It is known as the transferrin receptor and is composed of two disulfide-bonded 90 kD subunits. The CD71 molecule plays a critical role in cell proliferation by controlling the supply of iron, an essential component for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. CD71 protein is reported to be expressed on activated B and T cells, macrophages, proliferating cells and metabolically active cells, for example, neurons.
Specifications
Applications
IHC-P
Host
Mouse
Clonality
Monoclonal
Clone
10F11
Supplier
MONOSAN Xtra
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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