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Monosan goes Social!
You can find us now on LinkedIn, Twitter and we have launched a Blog with topics about Research & Diagnostics. Stay on top of the latest developments and technologies in Life Science and discuss with us about what is hot and what is not. We are pleased to share our ideas with you, but even more important: What are your ideas? Share your opinion with us!
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New Monosan products, anti-HGAL antibodies!
We are pleased to announce the release of HGAL for the detection of follicular lymphoma. This RUO antibody is available as concentrate or predilute (ready to use). Monosan's HGAL is compatible with most automated staining platforms.
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MONOSAN Xtra Detection Systems
The Monosan® Polymer Detection Systems utilize a novel controlled polymerization technology to prepare polymeric HRP-linker antibody conjugates. Therefore, the problem of non-specific staining that can occur with Streptavidin/Biotin detection systems due to endogenous biotin does not occur.
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NEW MONOSAN Xtra ANTIBODIES
CD19 Clone BT51E Cat. no. MONX11112
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. It is a single chain glycoprotein present on the surface of B lymphocytes and follicular dendritic cells of the hematopoietic system. CD19 is a crucial regulator in B cell development, activation and differentiation. On B cells, CD19 associates with CD21, CD81 and CD225 (Leu-13) forming a signal transduction complex. CD19 is expressed from the earliest recognizable B cell lineage stage, through development to B cell differentiation but is lost on maturation to plasma cells.
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CD166 in stem cell research applications
CD166 is highly expressed within the endogenous intestinal stem cell niche. CD166-positive cells appear at multiple stages of intestinal carcinoma progression, including benign and metastatic tumors. Further studies should investigate the function of CD166 in stem cells and the stem cell niche, which might have implications for normal intestinal homeostasis. CD166 has potential as a therapeutic target for CRC.
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